The vaginal estradiol cream will take several weeks for you to feel a difference in the amount of vaginal lubrication. In the meantime, consider trying vaginal lubricants and moisturizers to help with dryness.
Vaginal lubricants are a recommended first line treatment for mild vaginal dryness during sexual activity. Vaginal moisturizers can be used to help maintain vaginal moisture throughout the day. They help prevent itching and general discomfort. Vagainal moisturizers can be applied internally a few times per week and externally on a daily basis.