What Are the Most Common Side Effects of SSRIs (like sertraline)?

The most common side effects of sertraline are:

  • Nausea
  • Diarrhea
  • Insomnia
  • Dry mouth
  • Dizziness
  • Fatigue
  • Drowsiness
  • Tremor
  • Dyspepsia
  • Hyperhidrosis (excessive sweating)
  • Ejaculatory dysfunction
  • Erectile dysfunction
  • Decreased libido

Most of the side effects will go away with continued use of the medication, and most men tolerate the medicine well. There are many other potential side effects. For a complete list of side effects please see the PDR.

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