What Are the Common side Effects of Valacyclovir?

The most common side effects of valacyclovir include:

  • Headache (>10%)
  • Dizziness (1%-10%)
  • Vomiting(1%-10%)
  • Diarrhea (1%-10%)
  • Skin reaction after exposure to sunlight (photosensitivity) (1%-10%)
  • Rash (1%-10%)
  • Itching (pruritus) (1%-10%)

Less common reactions include:

  • Feeling confused (up to 1%)
  • Seeing or hearing things that aren’t there (hallucinations) (up to 1%)
  • Feeling very drowsy (up to 1%)
  • Tremors (up to 1%)
  • Feeling agitated (up to 1%)
  • Shortness of breath
  • Low back pain
  • Blood in urine (hematuria)

 

These nervous system side effects usually occur in people with kidney problems, the elderly (people over 65), or in organ transplant patients taking high doses of 8 grams or more of Valtrex a day. They usually get better when Valtrex is stopped or the dose reduced.

 

Very rare side effects include:

  • Unsteadiness when walking and lack of coordination (ataxia)
  • Slow
  • Slurred speech (dysarthria)
  • Fits (convulsions)
  • Altered brain function (encephalopathy)
  • Unconsciousness (coma)
  • Confused or disturbed thoughts (delirium)

These nervous system side effects usually occur in people with kidney problems, the elderly (people over 65), or in organ transplant patients taking high doses of 8 grams or more of Valtrex a day. They usually get better when Valtrex is stopped or the dose reduced.

Life threatening allergic reactions (anaphylaxis) are rare from valacyclovir. Stop taking valacyclovir and seek emergency medical treatment if you develop rapid development of flushing, itchy skin rash, swelling of the lips, face, neck, and throat—causing difficulty in breathing (angioedema), or fall in blood pressure leading to collapse.

 

This information is not, nor is it intended to be, a substitute for professional medical advice, diagnosis, or treatment, and should never be relied upon for specific medical advice. If you have any questions or concerns, please talk to your doctor.  

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