Does Bupropion (Zyban) Increase the Risk of Suicidal Thoughts?

All antidepressants, including bupropion, have a warning that they can increase suicidal thoughts. In adults this is less common. This medication should not be used in children for the purpose of smoking cessation. Even up to the age of 24, patients have an increased likelihood of having suicidal thoughts, especially when they start the medication.


Although suicidal thoughts are not a common side effect of bupropion for smoking cessation, it is very important to tell your doctor if you have a history of depression, suicidal thoughts or attempts, or any psychiatric history. If you develop suicidal thoughts while taking bupropion to  help you quit smoking, tell your doctor immediately so that it can be addressed. In adults, the benefits of using bupropion for smoking cessation are said to outweigh the risks—but that is when looking at the problem within a population. For an individual, for one person, serious side effects will outweigh a benefit. The medication should be stopped for any serious side effect and medical assistance sought immediately.  


This information is not, nor is it intended to be, a substitute for professional medical advice, diagnosis, or treatment, and should never be relied upon for specific medical advice. If you have any questions or concerns, please talk to your doctor.  

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