Can Bupropion (generic for Zyban) Affect a Urine Screening Test?

Yes. Sometimes bupropion is misidentified on urine screening tests as being an amphetamine, which it is not. In fact, one study noted, “Therapeutic use of bupropion appears to be the most frequent cause of false positive urine drug screens for amphetamines in our population.” If you are being screened for any reason, inform them that an alternate way of testing the urine should be done (e.g., gas chromatography/mass spectrometry).

 

This information is not, nor is it intended to be, a substitute for professional medical advice, diagnosis, or treatment, and should never be relied upon for specific medical advice. If you have any questions or concerns, please talk to your doctor.  

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