Antifungals (Ketoconazole, Sporanox, Itraconazole)

Antifungals (Ketoconazole, Sporanox, Itraconazole)

Certain antifungals such as itraconazole (Sporanox) and ketoconazole interact strongly with PDE 5 inhibitors by decreasing their breakdown thus leading to higher blood levels.

These drugs are used for fungal infections of the skin, nails, lungs (pneumonia), and central nervous system (fungal meningitis).

All oral ED medications need dose reductions if you are taking these antifungals for anything.

Please discuss with your doctor any antifungals and any other medications you are taking before beginning your ED medication. This includes OTC medications, vitamins, herbal remedies, etc.

Note: this list is not exhaustive.

This information is not, nor is it intended to be, a substitute for professional medical advice, diagnosis, or treatment, and should never be relied upon for specific medical advice. If you have any questions or concerns, please talk to your doctor. 

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