Alpha Blockers: Can I still take PDE 5 inhibitors for ED?
There is a concern that the combination of alpha blockers and PDE 5 inhibitors can cause dangerously low blood pressure if taken together.
For this reason, it is recommended that patients on alpha blocker only being PDE 5 inhibitors if they have been on the alpha blocker for some time without any dizziness or low blood pressure problems and it has been prescribed by a physician.
In addition, it is recommended to start the PDE 5 inhibitors at the lowest dose initially (e.g. Viagra 25mg, sildenafil 20mg, Cialis 2.5mg or 5mg, or Levitra 2.5mg or 5mg). If that dose is tolerated well but it is not effective, the dose can be titrated upwards slowly and carefully in consultation with your physician.
In addition, it is recommended separating the dose of the alpha blocker and the ED medication by at least 4 hours.
This information is not, nor is it intended to be, a substitute for professional medical advice, diagnosis, or treatment, and should never be relied upon for specific medical advice. If you have any questions or concerns, please talk to your doctor.