HIV Medications and ED Meds

This is a very complicated subject and you should always consult with a doctor before taking ED medication if you are taking medication for HIV.

In general, there are 3 types of HIV medications that interact with ED medications.

1️⃣ Protease Inhibitors

These medicines all end in “-navir” and include indinavir (Crixivan), ritonavir (Norvir), atazanavir (Reyataz), and others. These medicines increase the level of ED medications and prolong their action in the body because they slow the breakdown of PDE 5 inhibitors. They require reduced dosing and less frequent dosing of ED medications.

2️⃣ NNRTIs

These medicines include efavirenz and nevirapine. They reduce the levels of PDE 5 inhibitors in the blood and may require maximal doses of ED medicines instead of standard doses (e.g. Viagra 100mg instead of Viagra 50mg).

3️⃣ “Boosters”

These medicines are used to “boost” the levels of other HIV medicines. There are 2 of them, ritonavir (Norvir) and cobicistat (Tybost). The issue is that they also increase the levels of the ED medication itself and therefore require lower doses and less frequent dosing.

Never use this list alone to make decisions about ED medications as the names of medicines can be confusing. Always consult your physician about taking ED meds while on an HIV regimen.

This information is not, nor is it intended to be, a substitute for professional medical advice, diagnosis, or treatment, and should never be relied upon for specific medical advice. If you have any questions or concerns, please talk to your doctor. 

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